Diabetes MODY:

report of four cases

Abstract

With the term diabetes MODY (Maturity Onset Diabetes of the Young) is called a heterogeneous group of monogenic diseases, which present in common a dysfunction of β cells. There are currently more than 800 mutations related to this type of diabetes. The most common is MODY 2 diabetes due to a mutation within the glucokinase gene. Its prevalence is estimated between 2-5% of non-insulin-dependent diabetes types. The present work describes four MODY diabetes mutations (three type 2 and one type 3) diagnosed in the Child Endocrinology Service of the Centenario Hospital of the city of Rosario, Santa Fe, Argentina.